The analysis of prognostic factors in endometrial cancer managed with surgical staging / 부인종양
Korean Journal of Gynecologic Oncology
; : 129-133, 2006.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-170737
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To determine pathologic variables associated with overall survival and disease free survival of patients with endometrial cancer.METHODS:
Survival of 81 endometrial cancer patients treated with primary surgery between January 1997 and December 2003 at our center was compared about various histopathologic variables. All patients underwent complete surgical staging including pelvic +/- paraaortic lymph node dissection. Survival analyses were performed by the Kaplan-Meier curves and the log-rank test. Independent prognostic factors were determined by Cox's proportional hazards model using likelihood-ratio statistics based on the conditional parameter estimate (Conditional).RESULTS:
With regard to disease free survival, univariate analysis revealed no significant differences in subgroups according to age category, grade and adjuvant radiotherapy. However, significant differences in disease free survival were found between stage I+II and stage III, and between endometrioid type and the others type. Among these significant subgroups, the Cox-proportional hazards model showed that stage was the only independent prognostic factor. There were no significant differences in the overall survival of patients in subgroups according to age category and adjuvant radiotherapy. But, significant differences in overall survival were found in subgroups according to stage, histology and grade. Multivariate analysis revealed that stage was the only independent significant adverse prognostic effect.CONCLUSION:
Our results showed that only stage was an independent prognostic factor of disease free survival and overall survival in endometrial cancer patients.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Modelos de Riscos Proporcionais
/
Análise Multivariada
/
Neoplasias do Endométrio
/
Radioterapia Adjuvante
/
Intervalo Livre de Doença
/
Excisão de Linfonodo
Tipo de estudo:
Estudo prognóstico
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Gynecologic Oncology
Ano de publicação:
2006
Tipo de documento:
Artigo