A Case of Phenytoin-Induced Early Onset Isolated Thrombocytopenia / 대한간질학회지
Journal of Korean Epilepsy Society
; : 77-79, 2002.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-174105
Biblioteca responsável:
WPRO
ABSTRACT
Phenytoin is useful medication in patients with seizure disorders. Hematologic side effects of phenytoin treatment are rare. Especially, isolated thrombocytopenia is very rare. This condition is presumably the result of an immune-mediated process caused by antiplatelet antibodies induced by a drug as a hapten. Thrombocytopenia as a side effect of the phenytoin treatment usually has been reported in adults. It generally occurs at 2 to 4 weeks after initiation of therapy and resolved at 2 to 28 days after discontinuation of the phenytoin. In our case, the thrombocytopenia developed on the 2nd day of therapy and resolved on the 4th day after discontinuation of the phenytoin. We report a 3-year-old girl who developed reversible thrombocytopenia during the phenytoin treatment.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fenitoína
/
Trombocitopenia
/
Epilepsia
/
Anticorpos
Limite:
Adulto
/
Criança, pré-escolar
/
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Journal of Korean Epilepsy Society
Ano de publicação:
2002
Tipo de documento:
Artigo