Use of Clozapine for Borderline Personality Disorder: A Case Report
Clinical Psychopharmacology and Neuroscience
; : 226-228, 2016.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-175038
Biblioteca responsável:
WPRO
ABSTRACT
Patients with borderline personality disorder (BPD) show significant impairment in functioning, particularly in the interpersonal and social domains. Prior reports suggest that clozapine may be effective in the management of BPD. We present the case of a patient with BPD who experienced persistent suicidal ideation and was treated with clozapine at a state psychiatric hospital. After treatment failure with other psychotropic medications, clozapine medication was initiated; not only did suicidal ideation cease, but social and professional functioning also greatly improved to the point of no longer requiring intensive levels of observation or restrictive procedures. Clozapine appears to be efficacious in the management of suicide attempts and self-injurious behavior. Moreover, it appears to be promising as a therapeutic measure for ameliorating the global functioning of patients with severe BPD. Larger, randomized, blinded, and controlled prospective studies are needed to confirm these findings and to determine optimal dosage.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ajustamento Social
/
Suicídio
/
Transtorno da Personalidade Borderline
/
Estudos Prospectivos
/
Comportamento Autodestrutivo
/
Falha de Tratamento
/
Clozapina
/
Ideação Suicida
/
Hospitais Psiquiátricos
Tipo de estudo:
Ensaio clínico controlado
/
Estudo observacional
Limite:
Humanos
Idioma:
Inglês
Revista:
Clinical Psychopharmacology and Neuroscience
Ano de publicação:
2016
Tipo de documento:
Artigo