Infliximab: Effective Therapy for Pustular Psoriasis
Annals of Dermatology
; : 149-150, 2003.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-177292
Biblioteca responsável:
WPRO
ABSTRACT
Pustular psoriasis is often resistant to the standard therapies used to treat psoriasis vulgaris. Methotrexate, acitretin, and cyclosporine have been reported to be beneficial in the treatment of both psoriasis vulgaris and pustular psoriasis. Unfortunately, these agents have many side effects, which frequently preclude their use, and their efficacy in pustular psoriasis is often limited. We report a patient with pustular psoriasis whose skin disease cleared after administration of infliximab, a chimeric IgG monoclonal antibody that specifically binds to human tumor necrosis factor alpha (TNF-α). Prior to treatment with infliximab, she had failed several therapeutic trials of both topical and systemic agents.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Psoríase
/
Dermatopatias
/
Imunoglobulina G
/
Metotrexato
/
Fator de Necrose Tumoral alfa
/
Ciclosporina
/
Acitretina
/
Infliximab
Limite:
Humanos
Idioma:
Inglês
Revista:
Annals of Dermatology
Ano de publicação:
2003
Tipo de documento:
Artigo