Comparison of Clinical Findings between Autoimmune Pancreatitis with Bile Duct Involvement and Primary Sclerosing Cholangitis / 대한소화기학회지
The Korean Journal of Gastroenterology
; : 104-111, 2006.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-180551
Biblioteca responsável:
WPRO
ABSTRACT
BACKGOUND/AIMS:
The involvement of bile ducts is frequently reported in autoimmune pancreatitis (AIP), which seem to have similar features to primary sclerosing cholangitis (PSC). Recent systematic comparative studies about these diseases are rare in Korea.METHODS:
We retrospectively analyzed 26 patients with AIP with bile duct involvement and 30 patients with classic PSC who were diagnosed during the last decade.RESULTS:
The mean age of patients was significantly higher in AIP than PSC at the time of diagnosis. There was a preponderance of men in both group, which was more prominent in AIP. The most common symptom in patients with AIP was jaundice, but PSC patients usually visited hospitals due to incidentally detected abnormal liver function tests. Most (26/31) of AIP had bile duct involvement. All of these patients showed narrowing of intrapancreatic common bile ducts and one patient exhibited hilar involvement as well. About 80% of PSC had both intra- and extrahepatic ducts involvement, and the characteristic features involve multifocal strictures. AIP patients showed improvement with steroid treatment, however, most PSC patients showed clinical deterioration.CONCLUSIONS:
The clinical and cholangiographic findings of patients with AIP and PSC have many different characteristics. Therefore, further study of two diseases is required for the proper diagnosis and management.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pancreatite
/
Doenças Autoimunes
/
Ductos Biliares
/
Imunoglobulinas
/
Colangiografia
/
Colangite Esclerosante
/
Fatores Sexuais
/
Estudos Retrospectivos
/
Colangiopancreatografia Retrógrada Endoscópica
/
Diagnóstico Diferencial
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
The Korean Journal of Gastroenterology
Ano de publicação:
2006
Tipo de documento:
Artigo