Polyomavirus Disease in Kidney Transplantation / 대한이식학회지
The Journal of the Korean Society for Transplantation
; : 13-20, 2008.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-180624
Biblioteca responsável:
WPRO
ABSTRACT
Polyomavirus disease is a re-emerging infectious complication in renal transplantation. It manifests as symptomless renal dysfunction and progresses to graft loss unless the prompt diagnosis and intervention are initiated. A gold standard for diagnosis is the renal biopsy. Recently, the molecular diagnosis can be made using plasma PCR technique before histologic confirmation. Reduction of immunosuppression is a mainstay of treatment. Leflunomide and other antiviral agents could be used successfully in selected cases. The screening using urine decoy cell and subsequent plasma PCR may detect the BK viral replication, and preemptive intervention will prevent development of overt nephropathy without risk of rejection. This review will cover the recent advances and clinical issues in diagnosis and management of polyomavirus disease, mainly BK virus associated nephropathy.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Antivirais
/
Plasma
/
Rejeição em Psicologia
/
Biópsia
/
Programas de Rastreamento
/
Reação em Cadeia da Polimerase
/
Terapia de Imunossupressão
/
Transplante de Rim
/
Polyomavirus
/
Vírus BK
Tipo de estudo:
Estudo de rastreamento
Idioma:
Coreano
Revista:
The Journal of the Korean Society for Transplantation
Ano de publicação:
2008
Tipo de documento:
Artigo