Therapeutic Effect of Minocycline on Confluent and Reticulated Papillomatosis / 대한피부과학회지
Korean Journal of Dermatology
; : 204-209, 1998.
Article
em Ko
| WPRIM
| ID: wpr-180957
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND: Confluent and reticulate papillomatosis(CRP) of Gougerot and Carteaud is an uncommon disorder of unknown cause for which a variety of treatments have been proposed. OBJECTIVE: We attempted to evaluate the therapeutic effect of oral minocycline for CRP. METHOD: Nine patients(age range, 14 to 38; mean age, 21years) with CRP were included in this study. They took minocycline 100mg daily. The therapeutic effect was evaluated weekly by 5 scoring systems according to the percentage clearing of the skin lesion: poor (score 1), 95%. RESULTS: Two out of 9 patients showed complete clearing(score 5) of the skin lesions within 2 weeks. Seven patients revealed incomplete clearing(score 4) within 3 to 8 weeks. The mean scoring for 9 CRP patients was 4.2. Recurrences were noted in two patients at 24 and 26 months, respectively, but they responded to re-treatment with minocycline. The patients did not show any adverse reactions apart from two patients who developed mild pruritus. CONCLUSION: We recommend minocycline as the first choice of treatment for CRP because minocycline is safe, economic and effective.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Papiloma
/
Prurido
/
Recidiva
/
Pele
/
Minociclina
Limite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Dermatology
Ano de publicação:
1998
Tipo de documento:
Article