A Case of Steroid and Methotrexate-Resistant Eosinophilic Fasciitis Treated with Adalimumab
Journal of Rheumatic Diseases
; : 306-310, 2011.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-186126
Biblioteca responsável:
WPRO
ABSTRACT
Eosinophilic fasciitis (EF) is a rare fibrosing disorder characterized by painful swelling and induration of the limbs and trunk, characteristic histology with sclerosis and lymphocytic inflammation affecting the fascia. The cause and pathogenesis of EF are still unknown and current therapies include glucocorticoids with or without use of immunosuppressive agents. Recently, there have been several case reports documenting the efficacy of a TNF alpha inEosinophilic fasciitis (EF) is a rare fibrosing disorder characterized by painful swelling and induration of the limbs and trunk, characteristic histology with sclerosis and lymphocytic inflammation affecting the fascia. The cause and pathogenesis of EF are still unknown and current therapies include glucocorticoids with or without use of immunosuppressive agents. Recently, there have been several case reports documenting the efficacy of a TNF alpha inhibitor in EF following a steroid-resistant disease course. However, there has been no report on the experience in treatment of EF with a TNF alpha inhibitor in Korea. Hence, we report a case of steroid and methotrexate-resistant EF which was successfully treated with adalimumab, along with a review of the relevant articles.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Esclerose
/
Eosinofilia
/
Eosinófilos
/
Extremidades
/
Fáscia
/
Fasciite
/
Anticorpos Monoclonais Humanizados
/
Adalimumab
/
Glucocorticoides
/
Imunossupressores
País/Região como assunto:
Ásia
Idioma:
Coreano
Revista:
Journal of Rheumatic Diseases
Ano de publicação:
2011
Tipo de documento:
Artigo