Pulmonary Cryptococcosis in a Patient with Ankylosing Spondylitis treated with Etanercept
Journal of Rheumatic Diseases
; : 214-218, 2014.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-190173
Biblioteca responsável:
WPRO
ABSTRACT
Ankylosing spondylitis (AS) is a chronic inflammatory disorder, commonly characterized by inflammation of axial skeleton and development of enthesopathies. Tumor necrosis factor inhibitors (TNFi) shows good therapeutic responses in AS patients without good response to non-steroidal anti-inflammatory drugs. Although TNFi are relatively safe for AS patients, serious opportunistic infections, including tuberculosis and fungal infection, could develop. Here, according to our knowledge, we report a first Korean case of pulmonary cryptococcosis in a patient with AS treated with etanercept. A 64 year-old man with AS visited due to a newly appeared pulmonary nodule on a routine chest radiography. He had been administered etanercept for 5 months. Histologic findings of the lung nodule showed characteristic features of cryptococcosis. Etanercept was discontinued and oral fluconazole was administrated, as there was no evidence of central nervous system involvement. After 7 months of treatment, chest CT showed an improvement of the pulmonary lesion.
Texto completo:
Disponível
Contexto em Saúde:
Doenças Negligenciadas
Problema de saúde:
Doenças Negligenciadas
/
Tuberculose
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Esqueleto
/
Espondilite Anquilosante
/
Tórax
/
Tuberculose
/
Infecções Oportunistas
/
Radiografia
/
Tomografia Computadorizada por Raios X
/
Fluconazol
/
Sistema Nervoso Central
/
Doenças Reumáticas
Tipo de estudo:
Estudo diagnóstico
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of Rheumatic Diseases
Ano de publicação:
2014
Tipo de documento:
Artigo