Impact of Liver Fibrosis and Fatty Liver on T1rho Measurements: A Prospective Study
Korean Journal of Radiology
; : 898-905, 2017.
Article
em En
| WPRIM
| ID: wpr-191316
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE: To investigate the liver T1rho values for detecting fibrosis, and the potential impact of fatty liver on T1rho measurements. MATERIALS AND METHODS: This study included 18 healthy subjects, 18 patients with fatty liver, and 18 patients with liver fibrosis, who underwent T1rho MRI and mDIXON collections. Liver T1rho, proton density fat fraction (PDFF) and T2* values were measured and compared among the three groups. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the T1rho values for detecting liver fibrosis. Liver T1rho values were correlated with PDFF, T2* values and clinical data. RESULTS: Liver T1rho and PDFF values were significantly different (p 0.05). CONCLUSION: T1rho MRI is useful for noninvasive detection of liver fibrosis, and may not be affected with the presence of fatty liver.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Prótons
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Fibrose
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Imageamento por Ressonância Magnética
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Índice de Massa Corporal
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Estudos Prospectivos
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Curva ROC
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Fígado Gorduroso
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Voluntários Saudáveis
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Fígado
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Cirrose Hepática
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Korean Journal of Radiology
Ano de publicação:
2017
Tipo de documento:
Article