An Experimental Study on the Effect of Measurement Parameters and Hydrocephalus on the Pressure Volume Index

ABSTRACT

To study the effect of measurement parameters and hydrocephalus on the pressure volume index(PVI), PVI study was performed in 5 normal and 5 kaolin-induced hydrocephalic cats. The effects of injection volume, speed, laterality and influence of increased intracranial pressure(ICP) in normal and hydrocephalic cats on the PVI value were evaluated. The results were as follows; 1) Larger injection volume, increased ICP by continuous infusion, and presence of ventriculomegaly made the PVI value significantly higher(p<0.01, p<0.001, p<0.05, respectively). 2) Rapid injection made the PVI value significantly lower(p<0.01). 3) Increase of ICP accentuated the effects of injection volume and speed significantly(p<0.01). 4) There was no difference between the PVI values measured with injection into the ipsilateral lateral ventricle and those measured with injection into the cantralateral lateral ventricle. 5) With the above results, it is considered advisable to perform the PVI study with constant injection volume, speed and ICP.