The Clinicopathologic Characteristics of Lymphoid Tumor of The Orbit and Ocular Adnexa

ABSTRACT

The authors reivewed retrospectively the medical records and pathologic slides of 18 patients with the orbital lymphoid tumors that had been confirmed pathologically. Pathologic diagnoses were as follows 14 cases of pseudolymphoma (benign reactive hyperplasia), 2 cases of atypical lymphoid hyperplasia and 2 cases of malignant lymphoma. Of the 18 patients, 7 cases were male and 11 were female. The average age at first visit was 53 years. Palpable or visible mass was the most frequent presenting symptom. There were no significant differences in clinical characterstics and radiologic findings between benign and malignant tumors. Determination of clonality of tumors by immunohistochemical study was useful method to differentate pseudolymphoma and atypical lymphoid hyperplasia from malignant lymphoma. An accompanying systemic disease was not found in all cases. All patients were received local orbital irradiation. Regression or disappearance of masses was noted in all cases. No patient have experienced recurrence or development of systemic disease during the mean follow-up of 30 month.