The Therapeutic Effect of Drug in Parkinson's Disease
Journal of the Korean Neurological Association
; : 19-25, 1989.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-216342
Biblioteca responsável:
WPRO
ABSTRACT
Two hundred and four patients with Parkinson's disease initially treated wth a combination of levodopa and carbidopa ( Sinement 25-250 ) and / or anticholinergic drugs. All patients responded initially to drug. Sixteen patients(7.8%) had 20 acute central nervous system side effects 8, dyskinesia 6, visual hallucination5, psychosis and 1, akathisia. The response to treatment usually was stable for the first one and a half to four years of drug therapy. Subsequently, over 50 percent of patients had therapeutic failure among 82 patients with long term drug therapy, fourteen(l7.0%) had 18 side effects 8, on-off phenomenon 4. Morning dystonia 3, dyskinesiaand 3, simultaneous dyskinesia with parkinsonism. None had diphasic dyskinesia or myoclonus. The prognosis of the demented parkinsonian was relatively poor. Two patients died due to pneumonia and ovarian carcinoma.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Doença de Parkinson
/
Pneumonia
/
Prognóstico
/
Agitação Psicomotora
/
Transtornos Psicóticos
/
Carbidopa
/
Levodopa
/
Sistema Nervoso Central
/
Transtornos Parkinsonianos
/
Discinesias
Tipo de estudo:
Estudo prognóstico
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Neurological Association
Ano de publicação:
1989
Tipo de documento:
Artigo