Therapeutic Potential of Medicinal Plants and Their Constituents on Lung Inflammatory Disorders
Biomolecules & Therapeutics
; : 91-104, 2017.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-226873
Biblioteca responsável:
WPRO
ABSTRACT
Acute bronchitis and chronic obstructive pulmonary diseases (COPD) are essentially lung inflammatory disorders. Various plant extracts and their constituents showed therapeutic effects on several animal models of lung inflammation. These include coumarins, flavonoids, phenolics, iridoids, monoterpenes, diterpenes and triterpenoids. Some of them exerted inhibitory action mainly by inhibiting the mitogen-activated protein kinase pathway and nuclear transcription factor-κB activation. Especially, many flavonoid derivatives distinctly showed effectiveness on lung inflammation. In this review, the experimental data for plant extracts and their constituents showing therapeutic effectiveness on animal models of lung inflammation are summarized.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Plantas Medicinais
/
Pneumonia
/
Proteínas Quinases
/
Flavonoides
/
Bronquite
/
Extratos Vegetais
/
Fenol
/
Cumarínicos
/
Modelos Animais
/
Doença Pulmonar Obstrutiva Crônica
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Revista:
Biomolecules & Therapeutics
Ano de publicação:
2017
Tipo de documento:
Artigo