A case of vincristine-induced polyneuropathy in an patient with acute leukemia / 대한내과학회지
Korean Journal of Medicine
; : 611-616, 2009.
Article
em Ko
| WPRIM
| ID: wpr-227730
Biblioteca responsável:
WPRO
ABSTRACT
When neurological symptoms occur during the treatment of acute lymphoblastic leukemia, the differential diagnosis includes a leukemic infiltration of the nervous system, drug toxicity, infection, and other neurological disorders. We describe a 16-year-old girl with acute lymphoblastic leukemia that appeared to be complicated by vincristine-induced peripheral and cranial polyneuropathy after induction chemotherapy. She presented with right ptosis six weeks after the first dose of vincristine, and her neurological symptoms progressed to peripheral polyneuropathy. She recovered from these neurological symptoms over the next three months. Leukemic involvement of the nervous system and other neurological disorders could be excluded as potential causes of the neurological symptoms. This report shows that vincristine-induced neurotoxicity should be considered as a cause of cranial neuropathy that develops during the treatment of acute lymphoblastic leukemia.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Polineuropatias
/
Vincristina
/
Leucemia
/
Infiltração Leucêmica
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Doenças dos Nervos Cranianos
/
Diagnóstico Diferencial
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Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
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Quimioterapia de Indução
/
Sistema Nervoso
Tipo de estudo:
Diagnostic_studies
Limite:
Adolescent
/
Humans
Idioma:
Ko
Revista:
Korean Journal of Medicine
Ano de publicação:
2009
Tipo de documento:
Article