Ensulin Autoimmune Syndrome in a Patient with Methimazole-Treated Graves' Disease: A Case report / 대한내분비학회지
Journal of Korean Society of Endocrinology
; : 612-616, 1998.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-23013
Biblioteca responsável:
WPRO
ABSTRACT
Insulin autoimmune syndrome (IAS) includes fasting or reactive hypoglycemia, hyperinsulinemia and the presence of insulin-binding antibodies in patients who have never been exposed to exogenous insulin. This report concems a 29-year-old male patient with Graves disease who had history of having taken methimazole for two months, without any consequence, 6 months previously. However, when methimazole was administered again for three weeks, the patient suffered hypoglycemia during the next fourth week. He denied history of diabetes mellitus (DM), of taking any oral hypoglycemic agent or of having received insulin injection. Laboratory data showed total serum insulin level > 300 pu/mL, C-peptide reactivity (CPR) 8.0ng/mL and insulin antibody 89%. After stopping methimazole, he was treated with radioiodine (131I). There was no episode of hypoglycemic attack during 8 months of follow-up.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Peptídeo C
/
Doença de Graves
/
Seguimentos
/
Jejum
/
Diabetes Mellitus
/
Hiperinsulinismo
/
Hipoglicemia
/
Insulina
/
Metimazol
/
Anticorpos
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Journal of Korean Society of Endocrinology
Ano de publicação:
1998
Tipo de documento:
Artigo