Effect of yuquan pill on proinflammatory cytokines in patients with type 2 diabetes mellitus / 中国中西医结合杂志

ABSTRACT

<p><b>OBJECTIVE</b>To observe the effect of Yuquan Pill (YP) on proinflammatory cytokines in patients with type 2 diabetes mellitus (DM2).</p><p><b>METHODS</b>Ninety patients with DM2 were randomly divided into the treated group and the control group by the ratio of 21. Both groups were treated with Glucobay on the base of dietary and exercise therapy for 3 months, with YP, given to the treated group additionally 6 g four times a day. And the changes of proinflammatory cytokines, including C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), etc. were observed.</p><p><b>RESULTS</b>The levels of serum CRP,TNF-alpha and IL-6 significantly lowered after treatment in both groups (P<0.01), and the improvement in the treated group was superior to that in the control group (P<0.01).</p><p><b>CONCLUSION</b>YP could reduce the levels of the increased proinflammatory cytokines in patients with DM2.</p>