SOCS3: a potential therapeutic target for many human diseases / 药学学报
Acta Pharmaceutica Sinica
; (12): 747-752, 2011.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-233060
Biblioteca responsável:
WPRO
ABSTRACT
SOCS3 has significant regulation effects in cell signal transduction pathways, which can be induced by many kinds of cytokines and proinflammatory factors. After being studied for years, the effect of SOCS3 has become clear in maintaining physiological functions and affecting histopathologic changes in human tissues. This review presents the role of SOCS3 in the occurrence, development, diagnosis and treatment of human diseases, such as inflammation, virus infection, obesity and tumor. As abnormal levels or impaired function of SOCS3 were reported in the onset and development of disease, SOCS3 can be considered as a bio-marker to diagnose and predict prognosis of some disorders, and as a therapeutic target for certain diseases.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Viroses
/
Transdução de Sinais
/
Sistemas de Liberação de Medicamentos
/
Fator de Transcrição STAT3
/
Proteínas Supressoras da Sinalização de Citocina
/
Proteína 3 Supressora da Sinalização de Citocinas
/
Inflamação
/
Metabolismo
/
Neoplasias
/
Obesidade
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2011
Tipo de documento:
Artigo