Peripheral arterial disease in community-based patients with diabetes in Singapore: Results from a Primary Healthcare Study
Annals of the Academy of Medicine, Singapore
; : 525-527, 2010.
Article
em En
| WPRIM
| ID: wpr-234101
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>INTRODUCTION</b>Peripheral arterial disease (PAD) is an important complication of diabetes mellitus (DM), significantly associated with increased morbidity and mortality secondary to amputations, strokes and coronary artery disease. Information on DM patients with PAD is limited in our ethnically diverse population in Singapore. We aimed to determine the prevalence, risk factors and co-morbidities of PAD in patients managed for DM in the primary care setting.</p><p><b>MATERIALS AND METHODS</b>A cross-sectional study was conducted among 521 diabetics in 9 of the 18 government-aided clinics in the community. Data including demographics, presence of co-morbidities and vascular risk factors were collected using an interviewer-administered questionnaire, and Ankle-Brachial Index (ABI) was calculated from systolic ankle and brachial pressure measurements.</p><p><b>RESULTS</b>The prevalence of PAD, defi ned as resting ABI of <0.9 on either leg and/or a history of gangrene or non-traumatic amputation was 15.2% [95% confidence interval (CI), 12.3-18.5]. This prevalence of PAD was higher in patients with pre-existing microvascular and other macrovascular complications. In multivariate analysis, prevalence of PAD was positively associated with increasing age (OR, 1.08; 95% CI, 1.05-1.12), Malay versus Chinese ethnicity (OR, 2.27; 95% CI, 1.09-4.70), low HDL-cholesterol (OR, 1.87; 95% CI, 1.04- 3.37), and insulin treatment (OR, 2.98; 95%CI, 1.39-6.36).</p><p><b>CONCLUSION</b>PAD is an important cause of concern among patients with diabetes, with a high prevalence which further increases with increasing age and duration of DM, and exhibits ethnic variation. Risk factors identified in this study may improve early identification of PAD, allowing for prompt interventions, with a potential to reduce long-term morbidity and mortality.</p>
Texto completo:
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Base de dados:
WPRIM
Assunto principal:
Singapura
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China
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Epidemiologia
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Prevalência
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Distribuição por Sexo
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Distribuição por Idade
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Angiopatias Diabéticas
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Etnologia
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Doença Arterial Periférica
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Instituições de Assistência Ambulatorial
Tipo de estudo:
Observational_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Annals of the Academy of Medicine, Singapore
Ano de publicação:
2010
Tipo de documento:
Article