Correlation between serum growth differentiation factor-15 and TIMI risk scores in patients with unstable angina pectoris / 南方医科大学学报
Journal of Southern Medical University
; (12): 1277-1278, 2011.
Article
em Zh
| WPRIM
| ID: wpr-235144
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore the correlation between serum levels of growth differentiation factor-15 (GDF-15) and Thrombolysis in Myocardial Infarction (TIMI) risk scores in patients with unstable angina pectoris (UA).</p><p><b>METHODS</b>The serum levels of GDF-15 in 97 patients with UA and 30 healthy volunteers were measured using enzyme-linked immunosorbent assay (ELISA) and compared between 3 patient groups with different TIMI scores to analyze relationship between serum GDF-15 levels and TIMI risk scores.</p><p><b>RESULTS</b>The serum levels of GDF-15 in UA patients were significantly higher than those in the healthy volunteers (P<0.01). GDF-15 levels also differed significantly between patients with different TIMI scores (P<0.01), and showed a significant positive correlation to TIMI risk scores.</p><p><b>CONCLUSION</b>Serum levels of GDF-15 can be used as an index for evaluating the severity of UA.</p>
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Sangue
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Índice de Gravidade de Doença
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Terapia Trombolítica
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Medição de Risco
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Tratamento Farmacológico
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Fator 15 de Diferenciação de Crescimento
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Angina Instável
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Journal of Southern Medical University
Ano de publicação:
2011
Tipo de documento:
Article