Recent advances in natural product induced DNA damage response in cancer cells / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 4797-4804, 2015.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-236040
Biblioteca responsável:
WPRO
ABSTRACT
The DNA structures could be altered or even damaged by exogeous or endogenous factors during cell proliferation. Failure of effective and timely repair will lead to cell cycle arrest or apoptosis. By taking the advantage of the quick proliferation of cancer cells, DNA damage induction, cell cycle arrest and apoptosis promotion have become important strategies for ant-cancer chemotherapy. Previous reports showed that an array of natural compounds inhibit cancer cell proliferation by inducing DNA damage, which have therapeutic potentials for anti-cancer drug research and development.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Produtos Biológicos
/
Dano ao DNA
/
Medicamentos de Ervas Chinesas
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Neoplasias
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2015
Tipo de documento:
Artigo