Treatment of Epidermal Growth Factor Receptor Inhibitors Associated Adverse Skin Reactions by Zhiyang Pingfu Liquid: a Clinical Study / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 820-822, 2015.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-237932
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the curative effect of Zhiyang Pingfu Liquid (ZPL) in treating epidermal growth factor receptor inhibitors (EGFRIs) associated adverse reactions of the skin.</p><p><b>METHODS</b>All 54 patients with pathologically confirmed malignant tumor had EGFRIs induced adverse reactions of the skin to various degrees. ZPL was externally applied for them all, once or twice per day, 14 days consisting of one therapeutic course. Changes of adverse skin reactions, time for symptoms relief, adverse skin reaction types suitable for ZPL were observed before and after treatment.</p><p><b>RESULTS</b>EGFRIs associated skin adverse reactions were improved to various degrees after they used ZPL. The shortest symptoms relief time was 1 day while the longest was 12 days, with an average of 6.93 days and the median time 7 days. Compared with before treatment, itching, rash/scaling, acne/acneform eruptions were obviously improved (P < 0.05).</p><p><b>CONCLUSION</b>ZPL could alleviate EGFRls associated adverse skin reactions, especially showed better effect on itching, rash/scaling, acne/acneform eruptions.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prurido
/
Pele
/
Dermatopatias
/
Medicamentos de Ervas Chinesas
/
Pesquisa Biomédica
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Exantema
/
Receptores ErbB
/
Neoplasias
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Ano de publicação:
2015
Tipo de documento:
Artigo