Screening of specific miRNA in early gastric cancer / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
; (12): 175-179, 2014.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-239436
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To examine the micro-RNA (mirna) expression profile in tissues of early gastric cancer and to screen the specific mirna associated with gastric cancer.</p><p><b>METHODS</b>Gene chip technology was used to detect the expression of mirna in early gastric cancer tissues and adjacent normal tissues.</p><p><b>RESULTS</b>Compared to adjacent normal tissues, a total of 36 mirnas were down-regulated, such as mir-9-1, mir-103 and mir-141, while 12 mirnas were up-regulated, such as mir-196a, mir-142-3p and mir-25, etc.</p><p><b>CONCLUSION</b>Abnormal mirna expression level in early gastric cancer tissues may be associated to the development of gastric cancer.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias Gástricas
/
Regulação para Baixo
/
Regulação Neoplásica da Expressão Gênica
/
Regulação para Cima
/
Análise de Sequência com Séries de Oligonucleotídeos
/
MicroRNAs
/
Genética
Tipo de estudo:
Estudo diagnóstico
/
Estudo de rastreamento
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Gastrointestinal Surgery
Ano de publicação:
2014
Tipo de documento:
Artigo