Effect of shenfu injection on recovery of intestinal function, cellular immunity, serum interleukin-2 and tumor necrosis factor-alpha in children with intestinal obstruction after operation / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 744-746, 2003.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-240872
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the effect of Shenfu injection (SFI) on recovery of intestinal function, T-lymphocyte subsets (CD4, CD8 and CD4/CD8), interleukin-2 (IL-2) and tumor necrosis factor-alpha (TNF-alpha) in children with intestinal obstruction after surgical operation.</p><p><b>METHODS</b>Ninety-eight children suffering from intestinal obstruction after emergent surgical operation were divided into the SFI group (n = 50, treated with SFI after operation) and the control group (n = 48, treated with surgical operation alone). The intestinal function recovery rate (IFRR), T-lymphocyte subsets, serum levels of IL-2 and TNF-alpha in them were observed.</p><p><b>RESULTS</b>After being treated for 7 days, the IFRR in the SFI group was 84.0%, which was significantly higher than that in the control group (62.5%, P < 0.05). CD4, CD4/CD8 levels increased in the SFI group after treatment (P < 0.05), while in the control group, CD8 increased significantly after treatment (P < 0.05) and higher than that in SFI group (P < 0.01). IL-2 level was much higher in the SFI group after treatment than that in the control group (P < 0.05). TNF-alpha level significantly lowered in both groups (P < 0.01), and the level in the SFI group was lower than that in the control group (P < 0.05).</p><p><b>CONCLUSION</b>SFI could promote the recovery of intestinal function, improve and regulate the immune function of the children after operation for intestinal obstruction.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Período Pós-Operatório
/
Cirurgia Geral
/
Sangue
/
Medicamentos de Ervas Chinesas
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Interleucina-2
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Fator de Necrose Tumoral alfa
/
Relação CD4-CD8
/
Recuperação de Função Fisiológica
/
Usos Terapêuticos
/
Tratamento Farmacológico
Limite:
Criança, pré-escolar
/
Feminino
/
Humanos
/
Lactente
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Ano de publicação:
2003
Tipo de documento:
Artigo