Biosafety issues and public concerns on recombinant influenza viruses generated in the laboratories / 生物工程学报
Chinese Journal of Biotechnology
; (12): 1736-1742, 2013.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-242458
Biblioteca responsável:
WPRO
ABSTRACT
Understanding inter-species transmission of influenza viruses is an important research topic. Scientists try to identify and evaluate the functional factors determining the host range of influenza viruses by generating the recombinant viruses through reverse genetics in laboratories, which reveals the viruses' molecular mechanisms of infection and transmission in different species. Therefore, the reverse genetic method is a very important tool for further understanding the biology of influenza viruses and will provide the insight for the prevention and treatment of infections and transmission. However, these recombinant influenza viruses generated in laboratories will become the potential threat to the public health and the environment. In this paper, we discussed the biological safety issues of recombinant influenza viruses and suggested we should set up protocols for risk management on research activities related to recombinant highly pathogenic influenza viruses.
Texto completo:
Disponível
Contexto em Saúde:
ODS3- Meta 3D Reforçar a capacidade de alerta precoce, redução e gestão de riscos de saúde nacionais e globais
Problema de saúde:
Riscos Biológicos
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Orthomyxoviridae
/
Recombinação Genética
/
Segurança
/
Saúde Pública
/
Vírus Reordenados
/
Virus da Influenza A Subtipo H5N1
/
Genética
/
Laboratórios
/
Microbiologia
Tipo de estudo:
Guia de prática clínica
/
Estudo prognóstico
Aspecto:
Determinantes sociais da saúde
Idioma:
Chinês
Revista:
Chinese Journal of Biotechnology
Ano de publicação:
2013
Tipo de documento:
Artigo