Solid cystic papillary tumor of pancreas in eight children / 中国医学科学杂志(英文版)

ABSTRACT

<p><b>OBJECTIVE</b>To estimate the clinical and pathological features of pancreatic solid cystic papillary tumor (SCPT) in children.</p><p><b>METHODS</b>From 2000 to 2005, 8 cases with SCPT of the pancreas were analyzed retrospectively. All cases but one were females. Average age was 12.8 years. By case review, we discussed the clinical and pathological features of SCPT in children.</p><p><b>RESULTS</b>The chief complains were abdominal pain and palpable mass. There were 3 cases in the head, 1 case in the body, and 4 cases in the tail of pancreas. The procedures employed included local resection (1 case), distal pancreatectomy (5 cases), pancreaticoduodenectomy (1 case), and biopsy (1 case). Histological examination showed solid with cystic areas and papillary protrusions in the 8 cases; as for immunohistochemical examinations, the positive rate was 100% for alpha-antitrypsin (AACT), 87.5% for vinmentin, and 62.5% for neuron-specific enolase (NSE). The patients were followed up for 2 months to 4 years but one was lost by follow-up and all were alive postoperatively. SCPT in 2 cases relapsed.</p><p><b>CONCLUSION</b>Occurring predominantly in young females, SCPT is usually curable by surgical resection with a favorable prognosis.</p>