Y-chromosome-specific microsatellite variation in Li ethnic groups of Hainan Island, China / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 46-48, 2003.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-248503
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>The study was conducted to reveal the distribution of genetic polymorphism of four Y chromosome specific short tandem repeat (Y-specific STR) loci in Li ethnic groups in Hainan Island, China.</p><p><b>METHODS</b>Four tetranucleotide STR loci were simultaneously amplified with fluorescently labeled primers, and genotypes were determined with an automated DNA sequencer.</p><p><b>RESULTS</b>Among 230 unrelated males, the alleles at the four Y-specific STR loci were composed of some complex repeat structure. 4,5,4,5 alleles were observed in loci DYS3891, DYS390, DYS391, DYS393 respectively. A set of human allele ladders for the typing of the four Y-specific STRs was obtained in Li ethnic population. Gene diversity index (D) and haplotype diversity data were estimated for the four Y-STRs.</p><p><b>CONCLUSION</b>The preliminary study indicates a reference population for detecting male migration events and should be useful in population genetics and forensic applications.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Variação Genética
/
Haplótipos
/
DNA
/
Química
/
China
/
Análise de Sequência de DNA
/
Repetições de Microssatélites
/
Cromossomos Humanos Y
/
Frequência do Gene
/
Genética
Limite:
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Chinese Journal of Medical Genetics
Ano de publicação:
2003
Tipo de documento:
Artigo