Comparison of NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 in detecting HIV-1 viral load / 中华实验和临床病毒学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To compare the results of detecting HIV-1 load by using NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 assays.</p><p><b>METHODS</b>Eighty-two clinical samples were collected and HIV viral load was determined with the above-mentioned two methods.</p><p><b>RESULTS</b>The number of samples in which values obtained by NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 differed by <0.5 log10 RNA copies/ml and in which the viral load was undetectable accounted for 88.9 percent of the measures. The correlation coefficient between the two methods was 0.956 in 56 samples of Deltalog10 VL<0.5.</p><p><b>CONCLUSION</b>The results of HIV-1 viral load determination with the two methods are highly comparable.</p>