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Clinical characteristics and laboratory assay of adult Japanese encephalitis patients in an outbreak in Yuncheng, Shanxi Province, 2006 / 中华实验和临床病毒学杂志
Article em Zh | WPRIM | ID: wpr-254133
Biblioteca responsável: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the clinical and laboratory characteristics of adult Japanese encephalitis (JE) patients in a JE outbreak in Yuncheng, Shanxi Province in 2006.</p><p><b>METHOD</b>All the clinical data from the Second People's Hospital in Yuncheng city were analyzed, part of patients' sera and cerebrospinal fluid were tested by serology and RT-PCR.</p><p><b>RESULTS</b>The majority of patients were middle-aged and elderly, 77.8% (35/45) of the total cases were more than 40 years old. Severe and fulminating type cases accounted for 60.0% (27/45). Most patients had underlying diseases. IgM antibody to JE virus (JEV) in serum was positive in each of the 45 patients analyzed and 4-fold or greater rise in sera neutralization antibody titer were found in convalescent serum. JEV nucleic acid was positive in part of cerebrospinal fluid specimens.</p><p><b>CONCLUSION</b>Viral encephalitis emerged in Yuncheng city, Shanxi Province was Japanese encephalitis B, and most of the cases belonged to elderly group.</p>
Assuntos
Texto completo: 1 Base de dados: WPRIM Assunto principal: Sangue / Imunoglobulina M / RNA Viral / Testes de Neutralização / Líquido Cefalorraquidiano / China / Epidemiologia / Surtos de Doenças / Encefalite Japonesa / Reação em Cadeia da Polimerase Via Transcriptase Reversa Limite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Male País/Região como assunto: Asia Idioma: Zh Revista: Chinese Journal of Experimental and Clinical Virology Ano de publicação: 2008 Tipo de documento: Article
Texto completo: 1 Base de dados: WPRIM Assunto principal: Sangue / Imunoglobulina M / RNA Viral / Testes de Neutralização / Líquido Cefalorraquidiano / China / Epidemiologia / Surtos de Doenças / Encefalite Japonesa / Reação em Cadeia da Polimerase Via Transcriptase Reversa Limite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Male País/Região como assunto: Asia Idioma: Zh Revista: Chinese Journal of Experimental and Clinical Virology Ano de publicação: 2008 Tipo de documento: Article