Two cases of pancytopenia induced by ticlopidine / 대한내과학회지
Korean Journal of Medicine
; : S841-S843, 2003.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-25480
Biblioteca responsável:
WPRO
ABSTRACT
Ticlopidine is an inhibitor of platelet aggregation used in the management and prevention of thromboembolic disorders. Hematological toxicity is one of the most important side effects of ticlopidine, including neutropenia, thrombocytopenia and more seriously aplastic anemia. We reported here two cases of very severe aplastic anemia developed after the use of ticlopidine. Both patients suffered from an acute cerebral infarction. Both patients developed pancytopenia 56 days and 51 days after treatment with 500 mg of ticlopidine daily. Both patients were hospitalized and received empiric antibiotic therapy and G-CSF. Twenty-three days and thirty days after the withdrawal of ticlopidine, the hematologic parameters of each patient improved.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pancitopenia
/
Trombocitopenia
/
Ticlopidina
/
Infarto Cerebral
/
Agregação Plaquetária
/
Fator Estimulador de Colônias de Granulócitos
/
Anemia Aplástica
/
Neutropenia
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Ano de publicação:
2003
Tipo de documento:
Artigo