Drug Reaction with Eosinophilia and Systemic Symptom Syndrome Induced by Lamotrigine
Annals of Dermatology
; : 206-209, 2017.
Article
em En
| WPRIM
| ID: wpr-25584
Biblioteca responsável:
WPRO
ABSTRACT
Drug reaction with eosinophilia and systemic symptom (DRESS) syndrome is a type of severe adverse drug-induced reaction. Dermatologists should make a quick diagnosis and provide appropriate treatment for DRESS syndrome to reduce mortality rates, which can be as high as 10%. We present the case of a 47-year-old man with schizoaffective disorder treated with lamotrigine who developed DRESS syndrome to emphasize the importance of close observation of patients with drug eruption. He was consulted for erythematous maculopapular rashes on the trunk that developed 3 weeks after starting lamotrigine. A few days later, he developed generalized influenza-like symptoms. The skin rashes spread over his entire body, and the sense of itching was rapidly aggravated within a few days. Increased liver enzyme levels and significant eosinophilia were found on laboratory test results. His condition was diagnosed as DRESS syndrome, and he was treated with systemic and topical corticosteroids for 2 weeks.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Prurido
/
Transtornos Psicóticos
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Mortalidade
/
Corticosteroides
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Toxidermias
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Diagnóstico
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Eosinofilia
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Exantema
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Síndrome de Hipersensibilidade a Medicamentos
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Fígado
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Annals of Dermatology
Ano de publicação:
2017
Tipo de documento:
Article