Clinicopathological characteristics and prognosis of young esophageal cancer patients / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
; (12): 868-870, 2013.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-256902
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To compare the clinicopathological features and prognosis of esophageal cancer between young and elderly patients.</p><p><b>METHODS</b>Clinical data of 716 patients with esophageal squamous cell carcinoma undergoing curative operation from January 1990 to December 1998 at the Cancer Center of Sun Yat-sen University were analyzed retrospectively. Clinicopathological features and prognosis of 117 patients aged ≤45 years (young group) at diagnosis were compared with 599 patients aged >45 years (elderly group).</p><p><b>RESULTS</b>Except for tumor stage, there were no significant differences of clinicopathology between the young group and the elderly group (all P>0.05). There were more pathologic stage III cancer in the young group than the elderly group (47.9% vs. 33.6%, P=0.010). The 5-year survival rate (36.0% vs 33.8%) and 10-year survival rate (29.2% vs 25.0%) were not significantly different between the two groups (P=0.418). Multivariate analysis showed that the age was not the independent prognostic factors of esophageal squamous cell carcinoma (P=0.160, RR=1.187, 95%CI0.935-1.506).</p><p><b>CONCLUSION</b>Young esophageal cancer patients have more advanced tumors than elderly patients. However, the survival is comparable to the elderly.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Prognóstico
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Cirurgia Geral
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Neoplasias Esofágicas
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Carcinoma de Células Escamosas
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Modelos de Riscos Proporcionais
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Estudos Retrospectivos
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Fatores Etários
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Diagnóstico
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Estimativa de Kaplan-Meier
Tipo de estudo:
Estudo diagnóstico
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Estudo observacional
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Estudo prognóstico
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Fatores de risco
Limite:
Adulto
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Feminino
/
Humanos
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Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Gastrointestinal Surgery
Ano de publicação:
2013
Tipo de documento:
Artigo