Research advances in the application of methylprednisolone in the treatment of acute spinal cord injury / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 680-685, 2014.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-257694
Biblioteca responsável:
WPRO
ABSTRACT
Acute spinal cord injury(ASCI),mainly caused by traffic accidents and fall injuries,is a catastrophic event that can profoundly affect the trajectory of a patient's life. Debate continues over the medical management of ASCI,in particular the usefulness,dosage,and potential risks of methylprednisolone(MP). Although the results of American National Acute Spinal Cord Injury Study 2 and 3 trials led to the wide adoption of a high-dose MP regimen for ASCI patients,the reliabilities of their study methods and data were still questionable. Based on the currently available literature,we conclude that high-dose MP is no longer a recommended therapy for ASCI;however,due to the lack of effective treatment,it remains a useful option for this condition.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Traumatismos da Medula Espinal
/
Metilprednisolona
/
Ensaios Clínicos como Assunto
/
Resultado do Tratamento
/
Fármacos Neuroprotetores
/
Usos Terapêuticos
/
Tratamento Farmacológico
Limite:
Humanos
Idioma:
Inglês
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2014
Tipo de documento:
Artigo