The genetic polymorphism of 9 short tandem repeat loci in Yi ethnic group of Yunnan in China / 中华医学遗传学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the short teadem repeat(STR) genetics structure of a Chinese Yunnan Yi racial group.</p><p><b>METHODS</b>Genetic distributions for nine STR loci were determined based on STR gene scan marked by fluorescence.</p><p><b>RESULTS</b>Sixty-nine alleles and 164 kinds of genotypes were detected and identified from 84 unrelated Yi racial individuals. The corresponding gene and genotype frequencies were in 0.0060-0.5060 or 0.0119-0.4167 respectively. The expected and observed genotype frequencies of nine STR loci were in accordance with the Hardy-Weinberg equilibrium(P>0.05). The statistical analyses of nine STR loci showed that PIC was distributed in 0.5804-0.8777, H was in 0.6507-0.8002, DP was in 0.7976-0.9558, EPP was in 0.5207-0.8386, except TPOX and THO1 loci.</p><p><b>CONCLUSION</b>Above research data enrich the Chinese genetic database, and play an important role in Chinese genetic study and in forensic application.</p>