The influence on hemodynamics of myocardial ischemic dogs and blood pressure of animals with shenfu injection / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 259-262, 2003.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-266771
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the influence of Shenfu injection on the hemodynamic indexes of myocardial ischemic dogs and blood pressure of dogs and rats.</p><p><b>METHOD</b>Myocardial ischemic model was made and hypotension in the dogs was induced with ligating left front descending limb coronary artery method, and secondary hypertension by narrowing nephridium artery of rats, Shenfu injection was administered with 5, 10 mL.kg-1 to the above dogs and rats separately to investigate the influence of it on the hemodynamic indexes of myocardial ischemic dogs and blood pressure of rats.</p><p><b>RESULT AND CONCLUSION</b>Shenfu injection enhanced the capacity of myocardial work markedly; it augmented the myocardium contractility and cardiac output without raising the oxygen consume, and at the same time it returned normal the blood pressure in myocardial ischemic; but it had no effects on the normal blood pressure and secondary hypertension of rats.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Plantas Medicinais
/
Pressão Sanguínea
/
Medicamentos de Ervas Chinesas
/
Química
/
Ratos Sprague-Dawley
/
Isquemia Miocárdica
/
Aconitum
/
Ginsenosídeos
/
Tetra-Hidroisoquinolinas
Limite:
Animais
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2003
Tipo de documento:
Artigo