Clinical study of double filtration plasmapheresis for treatment of refractory myasthenia gravis / 南方医科大学学报
Journal of Southern Medical University
; (12): 355-357, 2007.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-268136
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To assess the therapeutic effect, timing of administration, complication prevention and management of the double filtration plasmapheresis (DFP) in the treatment of refractory myasthenia gravis (MG).</p><p><b>METHODS</b>Thirty-one patients with refractory MG were treated with KM 8800 membrane plasmapheresis monitor. DFP was performed every 3 days and the exchanging liquid was composed of 50 ml of 20% albumen and 1000 ml plasma substitute. Physical examination for absolute clinical score and blood sample was collected for AchR-Ab determination early in the morning on days 0, 3, 7, 14 of DFP.</p><p><b>RESULTS</b>With a total effective rate of 91.9%, complete recovery, basic recovery, improvement, and response was achieved in 2, 4, 11, and 17 patients, respectively, whereas the other 3 failed to respond. Hypotension occurred twice in 2 cases and was corrected after symptomatic treatment.</p><p><b>CONCLUSION</b>DFP may effectively lower blood AchR-Ab level of with minimal complications, and can be valuable for treatment of refractory MG.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Troca Plasmática
/
Autoanticorpos
/
Terapêutica
/
Sangue
/
Estudos Retrospectivos
/
Receptores Colinérgicos
/
Resultado do Tratamento
/
Alergia e Imunologia
/
Filtração
/
Métodos
Tipo de estudo:
Estudo observacional
Limite:
Adolescente
/
Adulto
/
Criança
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2007
Tipo de documento:
Artigo