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Influence of soy isoflavone on lindane cumulant in sprague-dawley rats / 生物医学与环境科学(英文)
Article em En | WPRIM | ID: wpr-270557
Biblioteca responsável: WPRO
ABSTRACT
Female Sprague-Dawley rats weighing 60-80 g were given different dosages of soy isoflavones and/or lindane for four weeks. Soy isoflavones was added in feed and lindane was given by oral gavage. We found that soy isoflavones could reduce the level of lindane in rat's serum and brain, but might cause the uterus hyperplasia. Lindane could inhibit the effect of soy isoflavones on uterus and significantly decrease the level of estradiol and testosterone in serum. This study indicated that soy isoflavones could reduce the level of lindane in rat's body. Lindane could reduce the level of hormones and decreased the effect of soy isoflavones on rat's uterus.
Assuntos
Texto completo: 1 Base de dados: WPRIM Assunto principal: Farmacologia / Glycine max / Testosterona / Útero / Hexaclorocicloexano / Sangue / Encéfalo / Química / Ratos Sprague-Dawley / Estradiol Limite: Animals Idioma: En Revista: Biomedical and Environmental Sciences Ano de publicação: 2014 Tipo de documento: Article
Texto completo: 1 Base de dados: WPRIM Assunto principal: Farmacologia / Glycine max / Testosterona / Útero / Hexaclorocicloexano / Sangue / Encéfalo / Química / Ratos Sprague-Dawley / Estradiol Limite: Animals Idioma: En Revista: Biomedical and Environmental Sciences Ano de publicação: 2014 Tipo de documento: Article