Study on applying chromatographic fingerprints to establishing quality criterion of processed tuber of Pinellia pedatisecta / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To explore the utility of principal component analysis (PCA) in conjunction with the window preprocessing scheme on chromatographic data for quality control.</p><p><b>METHOD</b>Chromatographic fingerprints of processed tuber of Pinellia pedatisecta were determined by HPLC, and the Window Preprocessing and PCA were used for data processing.</p><p><b>RESULT</b>The quantitative differences among different growing areas and different process batches were found with this method.</p><p><b>CONCLUSION</b>The method can be used in quality control for monitoring between-batch products of traditional Chinese pharmaceutical process.</p>