Progression of diabetic retinopathy: the Beijing Eye Study / 中华医学杂志(英文版)
Chinese Medical Journal
; (24): 3635-3640, 2011.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-274000
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>BACKGROUND</b>Diabetic retinopathy (DR) has emerged as a leading cause of visual impairment and blindness in the working-aged population worldwide. This study aimed to assess frequency and associated factors of progression of DR in subjects with known diabetes in a population-based setting.</p><p><b>METHODS</b>The Beijing Eye Study is a population based study performed in Greater Beijing in 2001 and 2006. The present investigation included all subjects with known diabetes mellitus in 2001, who participated in the follow-up examination in 2006. Fundus photographs were assessed.</p><p><b>RESULTS</b>The study included 170 subjects; 51 (30%) subjects showed signs of DR in 2001 and were re-examined in 2006, 36 (21.2%) subjects (18 subjects with DR present at baseline, 18 subjects with newly diagnosed DR in 2006) showed a progression of DR during follow-up. Progression of DR was associated with rural region (odds ratio (OR) 5.43, P = 0.001) and self-reported arterial hypertension (OR 3.85, P = 0.023). In the non-progressive subgroup, presence of DR was associated with different levels of education (< middle school, middle school, college or higher, OR 0.30, P = 0.023), treatment modes of diabetes mellitus (OR 10.24, P = 0.003) and cataract surgery (OR 9.14, P = 0.007).</p><p><b>CONCLUSIONS</b>In a population-based setting in Greater Beijing, progression of DR occurred in 35% of subjects with pre-existing DR and overall in 21% of subjects with known diabetes within a 5-year period. Progression of DR was significantly associated with rural region and self-reported arterial hypertension. In the stable subjects, presence of DR was significantly associated with poor educational level, insulin treatment of diabetes and cataract surgery.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
China
/
Epidemiologia
/
Análise Multivariada
/
Usos Terapêuticos
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Diabetes Mellitus
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Retinopatia Diabética
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Tratamento Farmacológico
/
Hipertensão
/
Insulina
Limite:
Adulto
/
Idoso
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Idoso, 80 anos ou mais
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Feminino
/
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Chinese Medical Journal
Ano de publicação:
2011
Tipo de documento:
Artigo