Cloning and expression of simplex herpes virus ? US4 fragment / 中华实验和临床病毒学杂志

ABSTRACT

<p><b>BACKGROUND</b>To get early laboratory study of type specific antigenicity of herpes simplex virus II.</p><p><b>METHODS</b>PCR and prokaryotic expression technique.</p><p><b>RESULTS</b>Herpes simplex virus II type specific gene fragment was expressed in E.coli and the products can be used as specific antigen for the detection of anti\HSV in the recovery sera.</p><p><b>CONCLUSIONS</b>Cloning and express of HSVII type specific antigen found the basis for developing specific diagnosis methods and vaccine of HSV.</p>