Radiofrequency ablation with or without transcather arterial chemoembolization for management of hepatocellular carcinoma / 南方医科大学学报
Journal of Southern Medical University
; (12): 1749-1751, 2007.
Article
em Zh
| WPRIM
| ID: wpr-281546
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the efficacy and complications of radiofrequency ablation (RFA) with or without transcatheter arterial chemoembolization (TACE) for management of hepatocellular carcinoma (HCC).</p><p><b>METHODS</b>A retrospective analysis was conducted for 62 small HCC cases undergoing RFA with or without TACE, and in each case, the tumors were not more than 3 with a diameter below 5 cm. Nineteen cases were managed with RFA alone (RFA group) while the other 27 underwent RFA combined with TACE (TACE+RFA group). Percutaneous RFA (RITA 1500) procedure was performed under CT guidance 1-3 weeks after TACE in TACE+RFA group.</p><p><b>RESULTS</b>The complete tumor necrosis rate was 77.8% (21/27) in TACE+RFA group, significantly higher than that in RFA group [57.9% (11/19), P<0.01], and the former group had a significantly lower local recurrence rate than the latter [22.2% (6/27) vs 42.1% (8/19), P<0.01]. Postoperative fever, local pain and temporary hepatic function abnormality were the common complications that were relieved after proper interventions, and mortality did not occur in these cases.</p><p><b>CONCLUSION</b>The combination of TACE and RFA significantly increases the complete tumor necrosis rate and decreases the recurrence rate of small HCC. CT-guided percutaneous RFA can be a safe and effective therapy for small HCC.</p>
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Terapêutica
/
Estudos Retrospectivos
/
Quimioembolização Terapêutica
/
Ablação por Cateter
/
Carcinoma Hepatocelular
/
Neoplasias Hepáticas
/
Métodos
Tipo de estudo:
Guideline
/
Observational_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
Idioma:
Zh
Revista:
Journal of Southern Medical University
Ano de publicação:
2007
Tipo de documento:
Article