Progressive transformation of lymph node germinal centers: a case report and literature review / 中华血液学杂志
Chinese Journal of Hematology
; (12): 253-256, 2010.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-283871
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To improve the understanding of progressive transformation of lymph node germinal centers (PTGC) and to explore its clinical, histopathologic and immunohistochemical features and the differential diagnosis between the related disease of germinal center hyperplasia.</p><p><b>METHODS</b>The clinical manifestation, laboratory bindings, treatment and outcome of a patient with PTGC were presented.</p><p><b>RESULTS</b>The main manifestation of the patient was painless peripheral lymphadenopathy. Histopathologic examination of an axillary lymph node showed reactive follicular hyperplasia and the progressive transformation changes germinal centers. The borderline between the germinal center and the mantle layer was obscured. The cells in the progressive transforming germinal centers were positive for CD20(+), CD5(+), CDw75(+).</p><p><b>CONCLUSION</b>PTGC is a rare lymphoid disorder. Histopathology and immunohistochemistry are important basis of the diagnosis.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Centro Germinativo
/
Diagnóstico Diferencial
/
Hiperplasia
/
Linfonodos
/
Doenças Linfáticas
Tipo de estudo:
Estudo diagnóstico
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Hematology
Ano de publicação:
2010
Tipo de documento:
Artigo