Functional neuro-navigation and intraoperative magnetic resonance imaging for the resection of gliomas involving eloquent language structures / 中华外科杂志
Chinese Journal of Surgery
; (12): 688-692, 2011.
Article
em Zh
| WPRIM
| ID: wpr-285663
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVES</b>To explore the clinical value of functional neuro-navigation and high-field-strength intraoperative magnetic resonance imaging (iMRI) for the resection of intracerebral gliomas involving eloquent language structures.</p><p><b>METHODS</b>From April 2009 to April 2010, 48 patients with intracerebral gliomas involving eloquent language structures, were operated with functional neuro-navigation and iMRI. Blood oxygen level dependent functional MRI (BOLD-fMRI) was used to depict both Broca and Wernicke cortex, while diffusion tensor imaging (DTI) based fiber tracking was used to delineate arcuate fasciculus. The reconstructed language structures were integrated into a navigation system, so that intra-operative microscopic-based functional neuro-navigation could be achieved. iMRI was used to update the images for both language structures and residual tumors. All patients were evaluated for language function pre-operatively and post-operatively upon short-term and long-term follow-up.</p><p><b>RESULTS</b>In all patients, functional neuro-navigation and iMRI were successfully achieved. In 38 cases (79.2%), gross total resection was accomplished, while in the rest 10 cases (20.8%), subtotal resection was achieved. Only 1 case (2.1%) developed long-term (more than 3 months) new language function deficits at post-operative follow-up. No peri-operative mortality was recorded.</p><p><b>CONCLUSIONS</b>With functional neuro-navigation and iMRI, the eloquent structures for language can be precisely located, while the resection size can be accurately evaluated intra-operatively. This technique is safe and helpful for preservation of language function.</p>
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Base de dados:
WPRIM
Assunto principal:
Cirurgia Geral
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Neoplasias Encefálicas
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Imageamento por Ressonância Magnética
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Córtex Cerebral
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Monitorização Intraoperatória
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Neuronavegação
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Glioma
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Métodos
Limite:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Surgery
Ano de publicação:
2011
Tipo de documento:
Article