Clinical and pathological features of IgA nephropathy in west Guangdong province / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To analyze the pathological and clinical features of IgA nephropathy (IgAN) in west Guangdong province.</p><p><b>METHODS</b>The pathological type and clinical features of 120 patients with IgAN were retrospectively analyzed.</p><p><b>RESULTS</b>Mesangial proliferative glomerulonephritis and focal segmental glomerulosclerosis were the most frequent features of IgAN. IgM deposit could be found in half of the IgAN patients, especially in the IgAN patients with focal segmental glomerulosclerosis.</p><p><b>CONCLUSION</b>The incidence of IgAN may vary between different regions. Clinically, misdiagnosis of other renal diseases as IgAN may often occur. The nature and severity of glomerular immunoglobulin deposition can be related to the pathogenesis and progression of IgAN.</p>