The distributing characteristics and proliferating activity of fibroblasts from the surrounding skin of keloids / 中华整形外科杂志
Chinese Journal of Plastic Surgery
; (6): 335-337, 2002.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-292067
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate whether there are abnormal fibroblasts derived from the surrounding skin of keloids so that a more accurate therapy for keloids could be obtained.</p><p><b>METHODS</b>Samples were taken for cell culture. When primary cells fully covered the culture bottle, the shape and distributing characteristics of fibroblasts were observed under the light microscope. 6-8 passage fibroblasts were selected for comparing the proliferating activity by MTT contrasting color method.</p><p><b>RESULTS</b>The fibroblasts have the same shape in all groups. But the fibroblasts derived from the surrounding skin grow crossly and overlapped just as the fibroblasts from keloids. The proliferating activity of the fibroblasts from surrounding skin is not as high as that from the border of keloids, but is higher than the normal skin fibroblasts derived either from a normal person or a patient with keloid.</p><p><b>CONCLUSION</b>It is likely that there are abnormal fibroblasts in the surrounding skin of keloids.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Pele
/
Divisão Celular
/
Células Cultivadas
/
Fibroblastos
/
Queloide
Limite:
Adolescente
/
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Plastic Surgery
Ano de publicação:
2002
Tipo de documento:
Artigo