The analysis of the factors for postoperative blood pressure recovery of aldosterone producing adenoma patients / 中华外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the factors regarding the recovery of postoperative blood pressure of aldosterone producing adenoma (APA) patients.</p><p><b>METHODS</b>Sixty-eight patients with APA were recruited and their data including retinal blood vessel by Doppler sonography, urinary trace albumin, pathological changes of renal biopsy and the adrenal tissues around the adenoma were analyzed in order to determine the correlation between these data and postoperative durative hypertension.</p><p><b>RESULTS</b>Postoperative durative hypertension occurred in 14 cases (41.2%) with increased resistance of unilateral or bilateral central artery of retina, in 16 cases (66.7%) with increased level of urinary trace albumin. Fifteen cases underwent renal biopsy and all of them showed different pathological alterations, 11 cases (73.3%) of which presented with postoperative durative hypertension. The pathological changes of the adrenal tissues around the adenoma is either atrophy or non-atrophy (normal or hyperplasia), 8 cases (40%) and 10 cases (22.2%) of which showed postoperative durative hypertension, respectively.</p><p><b>CONCLUSION</b>The renal pathological changes and increased resistance of retinal blood vessel are the main reasons leading to postoperative hypertension in patients with APA.</p>