Advances in application of adoptive T-cell therapy for cancer patients / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
; (6): 211-217, 2017.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-300802
Biblioteca responsável:
WPRO
ABSTRACT
Adoptive T-cell therapy is the administration of tumor cytotoxic T-cells derived from either patient himself or donors, which were induced or genetically engineered and expanded, and then injected into patients. Several strategies for adoptive T-cell therapy have been developed since last 30 years. From lymphokine-activated killer cells, tumor-infiltrating lymphocytes, cytokine-induced killer cells, to gene-modified T-cells and tumor associated antigen (TAA)-specific cytotoxic T-cells, the adoptive T-cell therapy has been moving forward to more precise tumor targeting and more effective in elimination of cancer cells. This article reviewed the advances of therapeutic approaches of adoptive T-cell therapy for cancer patients.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Zhejiang University. Medical sciences
Ano de publicação:
2017
Tipo de documento:
Artigo