Contraceptive effect of Curcuma longa (L.) in male albino rat / 亚洲男科学杂志(英文版)

ABSTRACT

<p><b>AIM</b>To study the contraceptive effect of the crude extracts of Curcuma longa in male albino rats.</p><p><b>METHODS</b>Rats were fed orally with Curcuma longa aqueous and 70% alcoholic extract for 60 days (500 mg x kg(-1) x day(-1)).</p><p><b>RESULTS</b>A reduction in sperm motility and density was observed in both the treated groups.</p><p><b>CONCLUSION</b>Curcuma longa may have affected the androgen synthesis either by inhibiting the Leydig cell function or the hypothalamus pituitary axis and as a result, spermatogenesis is arrested.</p>