Study complication of aplastic anemia following chemotherapy of acute myelogenous leukemia
Journal of Medical Research
; : 9-13, 2007.
Artigo
em Vietnamês
| WPRIM (Pacífico Ocidental)
| ID: wpr-303
Biblioteca responsável:
WPRO
ABSTRACT
Background:
Aplastic anemia following chemotherapy of acute leukemia is a common complication, which may lead to severe consequences.Objective:
To study characteristics of aplastic anemia occurred in ccute myelogenous leukemia (AML) patients, following chemotherapy. Subjects andmethods:
A prospective study was carried out in 50 AML patients treated at National Institute of Hematology and Blood Transfusion from Aug 2005 to Dec 2006. These patients were treated by induction chemotherapy with "3+7" regime.Result:
Aplastic anemia had been seen in 100% patients. Characteristics of this condition were poor marrow cells (average marrow cell count was 15.1\xb112.6 G/l) and strongly decreased counts of hemoglobin, white blood cells and platelets. Hemoglobin, white blood cell and platelet counts at the lowest level were 83.32 g/l; 0.96 G/l; 30.18 G/l; respectively. This situation prolonged for 3-4 weeks and changed into the most severe condition at the end of second week after chemotherapy. Infection frequency was 92%.Conclusion:
Aplastic anemia following chemotherapy of AML patients is a common complication with severe consequences such as significant decrease of WBC and platelet counts, which may lead to opportunistic infection. Hence, this complication must be monitored, detected and treated promptly. \r\n', u'\r\n', u'
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Leucemia
/
Tratamento Farmacológico
/
Anemia
Tipo de estudo:
Estudo observacional
Idioma:
Vietnamês
Revista:
Journal of Medical Research
Ano de publicação:
2007
Tipo de documento:
Artigo