Treatment and outcome of 14 children with hepatoblastoma / 中国当代儿科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To assess the outcome of childhood hepatoblastoma after a combination therapy of resection and chemotherapy.</p><p><b>METHODS</b>The clinical data of 14 children with hepatoblastoma was retrospectively reviewed. Their long-term survival was followed-up.</p><p><b>RESULTS</b>Twelve cases received surgery and planned chemotherapy. The follow-up duration averaged 18 months (range 1.5-74 months). Nine survived free of events, 1 died, 1 survived with multiple lung metastases, and 1 with increased alpha-fetoprotein (AFP) content but without residual tumor.</p><p><b>CONCLUSIONS</b>Surgery assisted with chemotherapy can improve the outcome of hepatoblastoma.</p>